Description

Microfilarial Sheath Matrix Protein 2 CAS NO 167473-79-2 is a specialized biochemical reagent of high purity, designed for advanced research and diagnostic applications. This protein plays a critical role in the structural integrity of parasitic microfilarial sheaths, making it an essential tool for studies in parasitology and tropical disease research. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic kit manufacturers focused on developing novel therapeutic and detection methods for filarial infections.

Application

• Research Reagent: Used as a key antigen in immunological and biochemical research to study the host-parasite interface in filarial diseases such as lymphatic filariasis and onchocerciasis.
• Diagnostic Development: Serves as a critical component in the development and validation of enzyme-linked immunosorbent assays (ELISA), lateral flow assays, and other immunodiagnostic platforms for specific pathogen detection.
• Vaccine Research: Investigated as a potential vaccine candidate or target antigen in preclinical studies aimed at inducing protective immunity against filarial nematodes.
• Drug Discovery: Employed in high-throughput screening assays to identify compounds that disrupt sheath formation or integrity, facilitating the discovery of novel anti-filarial agents.
• Reference Standard: Acts as a purified reference standard for quality control and calibration in diagnostic manufacturing and academic research laboratories.

Basic Information

Product Name	Microfilarial Sheath Matrix Protein 2
CAS No.	167473-79-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Sheath Matrix Protein 2; MSP-2; Filarial Sheath Antigen; Microfilarial Surface Protein 2; Onchocerca volvulus sheath antigen; Brugia malayi sheath protein; Diagnostic Antigen MSP2; Research Grade Sheath Protein
EINECS	Contact for details

Quality Control

Our Microfilarial Sheath Matrix Protein 2 is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes rigorous quality testing, including purity analysis by SDS-PAGE and HPLC, confirmation of immunological reactivity, and assessment of endotoxin levels. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and functional activity is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -70°C to -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use in a low-humidity environment.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Immunoblot)	Consistent with reference standard
Purity (SDS-PAGE)	≥ 90%
Protein Content (BCA)	≥ 95% of total weight
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (ELISA)	Reactive with specific antisera
Solubility	Soluble in PBS or suitable aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.