Description

Carbamic Acid, [(1S,3R)-3-Hydroxycyclopentyl]-, 1,1-Dimethylethyl Ester (9Ci) is a high-purity, chiral carbamate derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the production of complex, stereochemically defined molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of prostaglandin analogs and other bioactive molecules.
• API Development: Used as a protected precursor for introducing the cyclopentyl-hydroxy-carbamate moiety into target drug candidates.
• Asymmetric Synthesis: Employed in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a valuable scaffold for structure-activity relationship (SAR) studies and library synthesis.
• Process Chemistry: Integrated into scalable manufacturing routes for clinical trial materials and commercial APIs.
• Fine Chemical Production: Used in the custom synthesis of specialty chemicals requiring specific stereochemistry.

Basic Information

Product Name	Carbamic Acid, [(1S,3R)-3-Hydroxycyclopentyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	167465-99-8
Molecular Formula	C10H19NO3
Molecular Weight	201.26 g/mol
Synonyms	(1S,3R)-3-[(tert-Butoxycarbonyl)amino]cyclopentanol; tert-Butyl N-[(1S,3R)-3-hydroxycyclopentyl]carbamate; (1S,3R)-3-(Boc-amino)cyclopentanol; Boc-(1S,3R)-3-Aminocyclopentanol; (1S,3R)-3-Hydroxycyclopentylcarbamic acid tert-butyl ester; N-Boc-(1S,3R)-3-aminocyclopentanol; (1S,3R)-3-[(tert-Butoxycarbonyl)amino]cyclopentyl alcohol
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(1S,3R)-3-Hydroxycyclopentyl]-, 1,1-Dimethylethyl Ester (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% de
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.