Description

n-[(1S,2S)-2-Amino-1,2-Diphenylethyl]-1,1,1-Trifluoro-Methanesulfonamide is a high-purity, chiral triflamide derivative of significant value in asymmetric synthesis. This compound serves as a crucial chiral auxiliary or ligand for facilitating enantioselective transformations, enabling the production of optically pure intermediates. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• As a chiral auxiliary in asymmetric carbon-carbon and carbon-heteroatom bond-forming reactions.
• Utilized as a ligand precursor for transition metal catalysts in enantioselective hydrogenation and cross-coupling.
• Key intermediate in the synthetic pathways for complex pharmaceutical molecules and natural products.
• Employed in academic and industrial research for method development in stereoselective synthesis.
• Used in the preparation of specialty fine chemicals requiring high enantiomeric purity.

Basic Information

Product Name	n-[(1S,2S)-2-Amino-1,2-Diphenylethyl]-1,1,1-Trifluoro-Methanesulfonamide
CAS No.	167316-28-1
Molecular Formula	C15H15F3N2O2S
Molecular Weight	344.35 g/mol
Synonyms	(1S,2S)-N-(2-Amino-1,2-diphenylethyl)-1,1,1-trifluoromethanesulfonamide; (1S,2S)-1,2-Diphenyl-2-((trifluoromethyl)sulfonamido)ethanamine; (S,S)-TsDPEN Triflamide Derivative; (1S,2S)-N-(1,2-Diphenyl-2-aminoethyl)trifluoromethanesulfonamide; Chiral Triflyl Amine Derivative; (S,S)-Tf-DPEN; (1S,2S)-TfNH-DPEN
EINECS	Contact for details

Quality Control

Our n-[(1S,2S)-2-Amino-1,2-Diphenylethyl]-1,1,1-Trifluoro-Methanesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent oxidation and moisture uptake. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.