Description

Cyclopentanecarboxamide, n-Methoxy-n-Methyl- (9Ci) CAS NO 167303-65-3 is a specialized organic compound belonging to the class of Weinreb amides, which are pivotal intermediates in modern synthetic organic chemistry. Its primary value lies in its role as a highly effective acylating agent, enabling the controlled synthesis of ketones from various organometallic reagents with high selectivity and yield. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for introducing cyclopentyl carbonyl groups.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that incorporate cyclopentane-based motifs for enhanced biological activity.
• Organic Synthesis Reagent: Serves as a versatile Weinreb amide for the controlled formation of ketones via reactions with Grignard reagents, organolithiums, and other nucleophiles.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials where specific carbonyl functionality is required.
• Academic & R&D Laboratories: A critical reagent for methodological development and exploratory synthesis in university and industrial research settings.
• Fine Chemical Production: Utilized in the custom synthesis of specialty flavors, fragrances, and other high-value fine chemicals.

Basic Information

Product Name	Cyclopentanecarboxamide, n-Methoxy-n-Methyl- (9Ci)
CAS No.	167303-65-3
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	N-Methoxy-N-methylcyclopentanecarboxamide; Cyclopentanecarboxylic acid N-methoxy-N-methylamide; N-Methoxy-N-methylcyclopentane-1-carboxamide; N-Methoxy-N-methyl-1-cyclopentanecarboxamide; Weinreb amide of cyclopentanecarboxylic acid; N-Methoxy-N-methyl-cyclopentanecarboxamide; Cyclopentyl N-methoxy-N-methylcarboxamide; MCPCA
EINECS	Contact for details

Quality Control

Our production of Cyclopentanecarboxamide, n-Methoxy-n-Methyl- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistent performance. We provide detailed Certificates of Analysis (COA) with every shipment, documenting identity, assay, and impurity profiles. Our quality system is designed to support cGMP and ISO 9001 standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.