Description

Carbamic Acid, [(1S)-3-Oxocyclopentyl]-, 1,1-Dimethylethyl Ester (9Ci) is a specialized chiral building block of significant interest in advanced organic synthesis. This compound, identified by CAS number 167298-40-0, is valued for its role as a protected intermediate, enabling the controlled introduction of the cyclopentanone moiety into complex molecular architectures. It is primarily needed by research and development chemists and process scale-up teams within the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the construction of advanced, stereochemically defined active ingredients for crop protection products.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Peptidomimetic Chemistry: Employed in the synthesis of conformationally constrained peptide analogs and protease inhibitors.
• Natural Product Synthesis: A valuable intermediate for constructing complex natural products containing functionalized cyclopentane rings.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity chiral intermediates.

Basic Information

Product Name	Carbamic Acid, [(1S)-3-Oxocyclopentyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	167298-40-0
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	(1S)-3-Oxocyclopentylcarbamic acid tert-butyl ester; tert-Butyl N-[(1S)-3-oxocyclopentyl]carbamate; (S)-tert-Butyl (3-oxocyclopentyl)carbamate; (S)-3-Oxo-cyclopentylcarbamic acid tert-butyl ester; Boc-(S)-3-amino-cyclopentanone; (S)-Boc-3-aminocyclopentanone; (1S)-3-Oxocyclopentylcarbamic Acid 1,1-Dimethylethyl Ester; Carbamic acid, N-[(1S)-3-oxocyclopentyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(1S)-3-Oxocyclopentyl]-, 1,1-Dimethylethyl Ester (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D and process chemistry. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.