Description

D-Valine, 3-Methyl-, Methyl Ester, Hydrochloride is a chiral, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial, high-purity building block for the development of novel peptides, peptidomimetics, and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require enantiomerically pure intermediates for complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, including peptide-based drugs and enzyme inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a modified valine residue, influencing the peptide's conformation, stability, and biological activity.
• Biochemical Research: Employed as a standard or reagent in studies of enzyme mechanisms, metabolic pathways, and protein structure-function relationships.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in stereoselective chemical reactions to construct complex molecules with defined three-dimensional structures.
• Agrochemical Development: Potential use in the synthesis of chiral active ingredients for crop protection products.

Basic Information

Product Name	D-Valine, 3-Methyl-, Methyl Ester, Hydrochloride
CAS No.	167223-43-0
Molecular Formula	C7H16ClNO2
Molecular Weight	181.66 g/mol
Synonyms	Methyl (2R)-2-amino-3-methylbutanoate hydrochloride; D-3-Methylvaline methyl ester hydrochloride; (R)-2-Amino-3-methylbutanoic acid methyl ester hydrochloride; D-α-Aminoisovaleric acid methyl ester hydrochloride; Methyl D-2-amino-3-methylbutyrate hydrochloride; D-Valine methyl ester hydrochloride (3-methyl derivative); (R)-Methyl 2-amino-3-methylbutanoate hydrochloride
EINECS	Contact for details

Quality Control

Our D-Valine, 3-Methyl-, Methyl Ester, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent decomposition. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.