Description

R(-)-2-[2-(Diphenylphosphino)Phenyl]-4-Phenyl-2-Oxazoline is a chiral, bidentate P,N-ligand of significant importance in asymmetric catalysis. Its core value lies in enabling highly enantioselective transformations, which are critical for the efficient synthesis of single-enantiomer pharmaceuticals and fine chemicals. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• As a key chiral ligand in asymmetric hydrogenation reactions for pharmaceutical intermediates.
• Catalyst component for enantioselective C-C bond-forming reactions, such as cross-couplings and allylic substitutions.
• Use in the synthesis of optically active natural products and complex organic molecules.
• Research and development of novel transition metal catalysts for industrial-scale asymmetric processes.
• Production of chiral auxiliaries and building blocks for advanced material science.

Basic Information

Product Name	R(-)-2-[2-(Diphenylphosphino)Phenyl]-4-Phenyl-2-Oxazoline
CAS No.	167171-03-1
Molecular Formula	C27H22NOP
Molecular Weight	407.44 g/mol
Synonyms	(R)-2-[2-(Diphenylphosphino)phenyl]-4-phenyl-4,5-dihydrooxazole; (R)-2-[2-(Diphenylphosphino)phenyl]-4-phenyl-2-oxazoline; (R)-PHOX; (R)-2-(2-Diphenylphosphinophenyl)-4-phenyloxazoline; (R)-2-(2-Diphenylphosphanylphenyl)-4-phenyl-4,5-dihydrooxazole; (R)-2-(2-Diphenylphosphinophenyl)-4-phenyl-4,5-dihydrooxazole; (R)-2-(2-Diphenylphosphanylphenyl)-4-phenyl-2-oxazoline; (R)-2-(Diphenylphosphino)-2'-(4,5-dihydro-4-phenyloxazolyl)biphenyl
EINECS	Contact for details

Quality Control

Our production of R(-)-2-[2-(Diphenylphosphino)Phenyl]-4-Phenyl-2-Oxazoline adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high chiral purity. Every lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity (enantiomeric excess), chemical purity, and identity confirmation. We are committed to meeting the exacting standards required for catalyst and pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation and light, prolonged exposure to air or ambient light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.