Description

Band 3 Protein (547-553) (Human) is a synthetic peptide fragment corresponding to residues 547-553 of the human Band 3 anion transport protein, also known as Anion Exchanger 1 (AE1). This specific sequence is a critical epitope for research into erythrocyte membrane structure, function, and associated autoimmune disorders. It is an essential biochemical tool for scientists in immunology, hematology, and membrane biology. The product, identified by CAS No. 167095-71-8, is supplied to support high-purity research and diagnostic development.

Application

• Immunological Research: Used as an antigen in the study of autoimmune hemolytic anemias, particularly for investigating antibody responses against the Band 3 protein.
• Antibody Production & Characterization: Serves as a key immunogen or capture antigen for generating and screening monoclonal or polyclonal antibodies specific to the human Band 3 protein.
• Diagnostic Assay Development: Employed in the development and calibration of ELISA, Western blot, and other immunoassays for detecting autoantibodies in patient sera.
• Cell Biology Studies: Utilized in research exploring erythrocyte aging, senescence, and the role of Band 3 in cell membrane integrity and vesiculation.
• Biochemical Reagent: Acts as a competitive inhibitor or binding partner in studies of anion transport mechanisms and protein-protein interactions at the erythrocyte membrane.
• Quality Control Standard: Functions as a reference standard in the quality control of diagnostic kits targeting Band 3-related autoimmunity.

Basic Information

Item	Detail
Product Name	Band 3 Protein (547-553) (Human)
CAS No.	167095-71-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Anion Exchanger 1 Peptide (547-553); AE1 (547-553); Band 3 Anion Transport Protein Fragment; Erythrocyte Membrane Protein Band 3 Peptide; SLC4A1-derived peptide; Human Band 3 Cytoplasmic Fragment; Anion Exchange Protein 1 epitope
EINECS	Contact for details

Quality Control

Every batch of Band 3 Protein (547-553) (Human) is produced and analyzed under stringent conditions to ensure identity, purity, and consistency suitable for research applications. Our quality commitment includes comprehensive analytical characterization. Certificates of Analysis (COA) detailing purity (by HPLC), molecular weight confirmation (by Mass Spectrometry), and peptide content are provided with each shipment to guarantee traceability and meet your procurement standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Mass Spec)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Amino Acid Sequence	H-Lys-Glu-Glu-Val-Asp-Val-Tyr-OH (KEEVDVY)
Solubility	Soluble in water or dilute aqueous acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.