Description

3-Pyrrolidinecarbonitrile,1-Methyl-4-(1-Propenyl)-,[3Alpha,4Alpha(E)]-(9Ci) is a specialized pyrrolidine derivative nitrile compound, serving as a high-value chiral building block in advanced organic synthesis. Its precise stereochemistry and functional groups make it a critical intermediate for constructing complex molecular architectures with defined spatial orientation. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require complex, stereodefined pyrrolidine structures.
• Academic and Industrial R&D: A valuable compound for methodological studies in organic chemistry, including new cyclization and functionalization reactions.

Basic Information

Product Name	3-Pyrrolidinecarbonitrile,1-Methyl-4-(1-Propenyl)-,[3Alpha,4Alpha(E)]-(9Ci)
CAS No.	166832-86-6
Molecular Formula	C9H14N2
Molecular Weight	150.22 g/mol
Synonyms	1-Methyl-4-[(1E)-prop-1-en-1-yl]-3-pyrrolidinecarbonitrile; (3α,4α,E)-1-Methyl-4-(1-propenyl)-3-pyrrolidinecarbonitrile; (E)-1-Methyl-4-(prop-1-en-1-yl)pyrrolidine-3-carbonitrile; 3-Cyano-1-methyl-4-[(E)-1-propenyl]pyrrolidine; Pyrrolidine-3-carbonitrile, 1-methyl-4-[(1E)-1-propenyl]-, (3R,4R)-rel-; A chiral pyrrolidine nitrile building block
EINECS	Contact for details

Quality Control

Our 3-Pyrrolidinecarbonitrile,1-Methyl-4-(1-Propenyl)-,[3Alpha,4Alpha(E)]-(9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.