Description

Cyclopropaneacetamide, α-Amino-1-(Methylthio)- is a specialized chiral building block featuring a cyclopropane ring fused with an amino acid-like structure. This compound matters for its role as a key intermediate in the synthesis of complex, biologically active molecules, offering unique three-dimensional geometry and functional handles for chemical modification. Pharmaceutical and agrochemical research organizations need it for developing new active ingredients, particularly in the areas of protease inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel drug candidates, especially protease inhibitors and enzyme modulators.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the cyclopropane moiety can enhance biological activity and stability.
• Peptidomimetics Research: Serves as a constrained, non-proteinogenic amino acid analog in the design of peptide-like compounds with improved metabolic stability.
• Chemical Biology Probes: Employed in the synthesis of tool compounds for studying enzyme mechanisms and protein-ligand interactions.
• Asymmetric Catalysis: Can be utilized as a ligand precursor or a chiral auxiliary in stereoselective synthetic transformations.
• Material Science Research: Potential building block for specialty polymers or functionalized surfaces requiring specific stereochemistry.

Basic Information

Product Name	Cyclopropaneacetamide, α-Amino-1-(Methylthio)-
CAS No.	166813-29-2
Molecular Formula	C6H11NOS
Molecular Weight	145.22 g/mol
Synonyms	1-Amino-1-(methylthio)cyclopropanecarboxamide; (1-Amino-1-methylsulfanyl-cyclopropyl)-carbamic acid; α-Amino-α-(methylthio)cyclopropaneacetamide; 1-Amino-1-(methylthio)cyclopropanecarboxylic acid amide; 1-Carbamoyl-1-(methylthio)cyclopropylamine; Cyclopropanecarboxamide, 1-amino-1-(methylthio)-; (Aminomethylsulfanylcyclopropyl)formamide
EINECS	Contact for details

Quality Control

Our Cyclopropaneacetamide, α-Amino-1-(Methylthio)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.