Description

(R)-Ornidazole CAS NO 166734-80-1 is the single enantiomer of the broad-spectrum nitroimidazole antibiotic and antiprotozoal agent, Ornidazole. This high-purity chiral intermediate is critical for the development and manufacturing of enantiomerically pure pharmaceutical compounds, offering superior specificity and potentially reduced side effects compared to the racemic mixture. It is primarily required by pharmaceutical R&D laboratories and API manufacturers focused on advanced anti-infective therapies, chiral switches, and novel drug delivery systems.

Application

• Chiral Pharmaceutical Intermediate: Serves as a key building block for the synthesis of enantiopure active pharmaceutical ingredients (APIs).
• Antiprotozoal Drug Development: Used in research and production of targeted treatments for amoebiasis, giardiasis, and trichomoniasis.
• Antibiotic Research: Employed in the development of new-generation nitroimidazole antibiotics against anaerobic bacteria.
• Chiral Switch Programs: Essential for converting racemic Ornidazole into a single-isomer drug to improve pharmacokinetic and safety profiles.
• Reference Standard: Used as a high-purity certified reference material (CRM) for analytical method development and quality control.
• Biochemical Research: Applied in studies investigating the mechanism of action of nitroimidazole compounds at the molecular level.

Basic Information

Product Name	(R)-Ornidazole
CAS No.	166734-80-1
Molecular Formula	C7H10ClN3O3
Molecular Weight	219.63 g/mol
Synonyms	(R)-1-Chloro-3-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol; (R)-Ornidazole; (R)-1-(3-Chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole; Dextro-Ornidazole; (R)-Tiberal; (2R)-1-Chloro-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol; (R)-Enantiomer of Ornidazole; (R)-α-(Chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol
EINECS	Contact for details

Quality Control

Our (R)-Ornidazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay by HPLC, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.