Description

2-Amino-3-Fluoro-Propan-1-Ol is a versatile fluorinated amino alcohol building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular structure, which combines a reactive amino group, a fluorine atom, and a hydroxyl group, enabling its use in the creation of complex, biologically active molecules. Pharmaceutical, agrochemical, and specialty chemical R&D teams need this high-purity intermediate for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of fluorinated drug candidates, including protease inhibitors and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel fluorinated pesticides and herbicides, where the fluorine atom can enhance bioavailability and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Incorporated into peptide backbones to modulate conformation, metabolic stability, and binding affinity.
• Fluorine-Containing Material Science: Employed in the development of specialty polymers, surface modifiers, and liquid crystals.
• Chemical Biology Probes: Useful for labeling and studying biological systems due to the fluorine atom's utility in 19F NMR spectroscopy.

Basic Information

Product Name	2-Amino-3-Fluoro-Propan-1-Ol
CAS No.	166665-93-6
Molecular Formula	C3H8FNO
Molecular Weight	93.10 g/mol
Synonyms	3-Fluoro-2-aminopropan-1-ol; 2-Amino-3-fluoropropanol; 3-Fluoro-2-aminopropanol; 1-Propanol, 2-amino-3-fluoro-; 2-Amino-3-fluoro-1-propanol; 3-Fluoroalaninol; (R/S)-2-Amino-3-fluoropropan-1-ol; (±)-2-Amino-3-fluoropropan-1-ol
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Fluoro-Propan-1-Ol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.