Description

tert-Butyl 2-(Bromomethyl)Phenylcarbamate is a versatile and high-purity chemical intermediate essential for advanced organic synthesis. This compound is valued for its reactive bromomethyl and protected carbamate functional groups, enabling precise molecular construction. It is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structure contributes to specific biological activity.
• Peptidomimetics & PROTACs: Serves as a crucial precursor in the design and synthesis of peptidomimetics and Proteolysis-Targeting Chimeras (PROTACs) for drug discovery.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Acts as a monomer or functionalization agent in the development of novel polymers and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	tert-Butyl 2-(Bromomethyl)Phenylcarbamate
CAS No.	166329-43-7
Molecular Formula	C12H16BrNO2
Molecular Weight	286.17 g/mol
Synonyms	2-(Bromomethyl)phenyl N-(tert-butoxycarbonyl)carbamate; tert-Butyl N-[2-(bromomethyl)phenyl]carbamate; Carbamic acid, N-[2-(bromomethyl)phenyl]-, 1,1-dimethylethyl ester; BOC-2-(Bromomethyl)aniline; N-Boc-2-(bromomethyl)aniline; 2-(Bromomethyl)aniline N-Boc derivative; (2-(Bromomethyl)phenyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 2-(Bromomethyl)Phenylcarbamate is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications, which are aligned with industry best practices for fine chemical intermediates. A detailed Certificate of Analysis (COA) documenting purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.