Description

2-Butanone, 1-Ethoxy-1,1-Difluoro-3-Methyl- is a specialized fluorinated ketone derivative, identified by CAS No. 165544-40-1, valued for its unique molecular structure that incorporates both ether and difluoromethyl groups. This compound is a critical highly volatile intermediate in advanced organic synthesis, enabling the introduction of fluorine atoms to enhance the properties of target molecules. It is primarily sought by pharmaceutical, agrochemical, and advanced materials research and development sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of fluorinated active pharmaceutical ingredients (APIs), where fluorine substitution can improve metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom to enhance biological activity and environmental persistence.
• Advanced Material Precursor: Serves as a monomer or modifier in the production of specialty polymers, coatings, and liquid crystals with tailored surface properties and chemical resistance.
• Organic Synthesis Reagent: Functions as a versatile reagent in academic and industrial R&D for constructing complex molecules via reactions involving its ketone and ether functionalities.
• Fluorine Chemistry Research: An essential compound for studying novel fluorination methodologies and the development of new organofluorine compounds.

Basic Information

Product Name	2-Butanone, 1-Ethoxy-1,1-Difluoro-3-Methyl-
CAS No.	165544-40-1
Molecular Formula	C7H12F2O2
Molecular Weight	166.17 g/mol
Synonyms	1-Ethoxy-1,1-difluoro-3-methylbutan-2-one; 3-Methyl-1-ethoxy-1,1-difluorobutan-2-one; 1,1-Difluoro-1-ethoxy-3-methyl-2-butanone; Ethyl 1,1-difluoro-3-methyl-2-oxobutyl ether; Difluoro(ethoxy)(3-methyl-2-oxobutyl)methane
EINECS	Contact for details

Quality Control

Every batch of 2-Butanone, 1-Ethoxy-1,1-Difluoro-3-Methyl- is produced and analyzed under a strict quality management system to ensure high purity and batch-to-batch consistency. Our products undergo rigorous quality testing, including advanced chromatographic methods, to ensure compliance with industry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from incompatible materials such as strong bases and other fluorides/strong alkalis. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 3.0%
Density (at 20°C)	~1.05 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.