Description

Pentanoic Acid, 3,3-Difluoro-2-Oxo- is a high-value fluorinated organic building block characterized by its reactive oxo and difluoro functional groups. This compound is essential for the synthesis of complex molecules where the introduction of fluorine atoms is critical for modulating biological activity, metabolic stability, and physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated active pharmaceutical ingredients (APIs), particularly in protease inhibitors and other small-molecule drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where fluorine substitution enhances efficacy and environmental profile.
• Material Science Research: Serves as a precursor for fluorinated polymers, liquid crystals, and specialty materials with unique surface properties.
• Organic Synthesis Building Block: Employed in medicinal and combinatorial chemistry for constructing complex molecular architectures via reactions at the ketone and acid functionalities.
• Biochemical Probe Development: Utilized in creating labeled compounds and probes for studying enzymatic mechanisms and metabolic pathways.

Basic Information

Product Name	Pentanoic Acid, 3,3-Difluoro-2-Oxo-
CAS No.	165544-38-7
Molecular Formula	C5H6F2O3
Molecular Weight	152.10 g/mol
Synonyms	3,3-Difluoro-2-oxopentanoic acid; 2-Oxo-3,3-difluoropentanoic acid; 3,3-Difluoro-2-ketopentanoic acid; 3,3-Difluorolevulinic acid; Difluorolevulinic acid; Levulinic acid, 3,3-difluoro-; α-Keto-3,3-difluoropentanoic acid
EINECS	Contact for details

Quality Control

Our production of Pentanoic Acid, 3,3-Difluoro-2-Oxo- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting cGMP development work where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to strong bases and fluorides; keep away from incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.