Description

tert-Butyl n-[2-(Prop-2-Enamido)Ethyl]Carbamate is a specialized, high-purity chemical intermediate designed for advanced organic synthesis. Its core value lies in its bifunctional structure, incorporating both a protected amine and a polymerizable acrylamide group, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require reliable building blocks for creating novel polymers, peptide mimetics, and targeted drug conjugates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a protected aminoethyl spacer.
• Polymer Chemistry & Hydrogel Synthesis: Serves as a functional monomer for creating smart polymers, responsive hydrogels, and biocompatible materials via free-radical or controlled polymerization.
• Peptidomimetics & Bioconjugation: Used to introduce stable amide linkages and spacer arms in the design of peptide analogs and for the site-specific conjugation of drugs to antibodies or polymers.
• Surface Functionalization: Enables the covalent attachment of bioactive molecules to surfaces (e.g., medical devices, biosensors, chromatography media) through its reactive acrylamide group.
• Cross-linking Agent: Acts as a cross-linker in the production of three-dimensional polymer networks with tailored mechanical and swelling properties.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic pathways and material properties.

Basic Information

Item	Details
Product Name	tert-Butyl n-[2-(Prop-2-Enamido)Ethyl]Carbamate
CAS No.	165196-44-1
Molecular Formula	C10H18N2O3
Molecular Weight	214.26 g/mol
Synonyms	N-(2-((tert-Butoxycarbonyl)amino)ethyl)acrylamide; N-(2-(Boc-amino)ethyl)acrylamide; Boc-NH-(CH2)2-NH-CO-CH=CH2; 2-[(tert-Butoxycarbonyl)amino]ethylacrylamide; Acrylamide, N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-; tert-Butyl (2-acrylamidoethyl)carbamate; Boc-AEA-OH (acrylamide derivative)
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[2-(Prop-2-Enamido)Ethyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.