Description

4-Androsten-17A-Ol-3-One-2,2,4,6,6-D5 is a deuterated analog of a key steroid intermediate, offering a stable isotope-labeled standard for advanced analytical and research applications. This high-purity compound is essential for ensuring accuracy and reliability in quantitative mass spectrometry and metabolic studies. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers working on method development, pharmacokinetics, and bioanalytical assays.

Application

• Internal Standard for LC-MS/MS: Serves as a critical stable isotope-labeled internal standard in quantitative bioanalysis for drug metabolism and pharmacokinetic (DMPK) studies.
• Metabolic Pathway Research: Used as a tracer to investigate steroid biosynthesis, metabolism, and degradation pathways in biochemical research.
• Pharmaceutical Reference Standard: Employed as a certified reference material (CRM) for the calibration and validation of analytical methods in quality control laboratories.
• Doping Control Analysis: Applied in sports anti-doping laboratories for the precise detection and quantification of endogenous steroids and their metabolites.
• Clinical Diagnostics: Supports the development of highly accurate diagnostic assays for endocrine disorders and hormone level monitoring.

Basic Information

Item	Details
Product Name	4-Androsten-17A-Ol-3-One-2,2,4,6,6-D5
CAS No.	165195-35-7
Molecular Formula	C19H25D5O2
Molecular Weight	291.48 g/mol (approx.)
Synonyms	Androst-4-ene-17α-ol-3-one-2,2,4,6,6-d5; 17α-Hydroxyandrost-4-en-3-one-d5; 17α-Hydroxy-4-androsten-3-one-d5; 17α-Hydroxyandrost-4-en-3-one-2,2,4,6,6-d5; Deuterated Epitestosterone; Epitestosterone-d5; 17α-Testosterone-d5; 4,17α-Dihydroxyandrost-4-en-3-one-d5
EINECS	Contact for details

Quality Control

Every batch of 4-Androsten-17A-Ol-3-One-2,2,4,6,6-D5 is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to support its use as a reference standard, including confirmation of isotopic purity and chemical identity. Certificates of Analysis (COA) detailing specifications such as assay by HPLC, isotopic enrichment by MS, and related substance profiles are available upon request to ensure full traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which could affect stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (by HPLC)	≥ 95.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.