Description

7-(Trifluoromethyl)Isochroman CAS NO 165115-37-7 is a high-value fluorinated heterocyclic building block, prized for its unique chemical structure that imparts enhanced metabolic stability and lipophilicity to target molecules. Its core value lies in enabling the synthesis of novel compounds with improved biological activity and physical properties. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, where the introduction of a trifluoromethyl group is a critical design strategy.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research programs.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides, where the CF3 group improves efficacy and environmental profile.
• Material Science Research: Serves as a precursor for fluorinated polymers and liquid crystals, contributing to materials with unique thermal and optical properties.
• Organic Synthesis Building Block: Employed in medicinal chemistry for scaffold decoration and in academic research for method development involving fluorinated isochromans.
• Fluorine Chemistry Studies: A valuable compound for investigating structure-activity relationships (SAR) and the effects of fluorine substitution in heterocyclic systems.

Basic Information

Product Name	7-(Trifluoromethyl)Isochroman
CAS No.	165115-37-7
Molecular Formula	C10H9F3O
Molecular Weight	202.17 g/mol
Synonyms	7-(Trifluoromethyl)-3,4-dihydro-1H-isochromene; 7-(Trifluoromethyl)-3,4-dihydro-2H-isochromene; 7-(Trifluoromethyl)-1,2,3,4-tetrahydroisochromene; 7-Trifluoromethylisochroman; Isochroman, 7-(trifluoromethyl)-; 165115-37-7
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)Isochroman is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade starting materials and research-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.