Description

Becaplermin is a recombinant human platelet-derived growth factor (rhPDGF-BB) used for topical wound healing. This biologically active protein is critical in advanced therapeutic applications, particularly for stimulating tissue regeneration. It is primarily utilized by pharmaceutical manufacturers and research institutions developing treatments for chronic wounds, such as diabetic foot ulcers.

Application

• Active Pharmaceutical Ingredient (API) in topical gel formulations for wound healing.
• Diabetic Foot Ulcer Treatment as the key therapeutic agent in prescription medications.
• Biomedical Research for studying cell proliferation, angiogenesis, and tissue repair mechanisms.
• Regenerative Medicine development, including advanced wound dressings and tissue engineering scaffolds.
• Clinical Research for investigating new therapeutic applications in dermatology and surgery.

Basic Information

Product Name	Becaplermin
CAS No.	165101-51-9
Molecular Formula	C785H1233N223O235S6
Molecular Weight	Approx. 17,500 Da
Synonyms	Recombinant Human Platelet-Derived Growth Factor BB; rhPDGF-BB; Regranex; Platelet-Derived Growth Factor, Human Recombinant; PDGF-BB; PDGF, Human; PDGF Homodimer BB; Becaplermin Recombinant; Growth Factor BB, Platelet-Derived
EINECS	Contact for details

Quality Control

Our Becaplermin is manufactured under strict quality systems suitable for pharmaceutical applications. The product undergoes rigorous analytical testing to ensure identity, purity, potency, and safety, aligning with ICH guidelines. A comprehensive Certificate of Analysis (COA) detailing purity, biological activity, endotoxin levels, and related substances is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under controlled conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Biological Activity (Cell-based assay)	≥ 1.0 x 105 units/mg
Endotoxin	< 1.0 EU/mg
Moisture Content (KF)	≤ 3.0%
Related Proteins (HPLC)	Meets acceptance criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.