Description

(3S,3As,5As,6R,9As,9Bs)-3-[[[2,5-Bis(Trifluoromethyl)Phenyl]Amino]Carbonyl]Dodecahydro-3A,6-Dimethyl-7-Oxo-1H-Benz[E]Indene-6-Propanoic Acid is a high-purity, complex organic compound featuring a benz[e]indene core structure with a trifluoromethyl-substituted phenylamino carbonyl moiety. This compound matters as a sophisticated chemical intermediate and pharmacological research tool, valued for its unique steric and electronic properties imparted by the fluorine atoms. It is primarily needed by pharmaceutical R&D teams and advanced organic synthesis laboratories for developing novel active ingredients and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Advanced Organic Synthesis: Serves as a specialized intermediate for synthesizing complex, polycyclic organic molecules in academic and industrial research settings.
• Fluorinated Compound Library: A valuable component for creating libraries of fluorinated compounds to screen for novel biological activities.
• Biochemical Probe Development: Potential use in designing probes to study enzyme interactions or cellular pathways due to its specific structural features.
• Material Science Research: Investigated as a precursor for advanced organic materials where fluorinated aromatic systems are advantageous.

Basic Information

Item	Details
Product Name	(3S,3As,5As,6R,9As,9Bs)-3-[[[2,5-Bis(Trifluoromethyl)Phenyl]Amino]Carbonyl]Dodecahydro-3A,6-Dimethyl-7-Oxo-1H-Benz[E]Indene-6-Propanoic Acid
CAS No.	164656-20-6
Molecular Formula	C28H29F6NO4
Molecular Weight	557.53 g/mol
Synonyms	3-[[[2,5-Bis(trifluoromethyl)phenyl]amino]carbonyl]dodecahydro-3a,6-dimethyl-7-oxo-1H-benz[e]indene-6-propanoic acid; (3S,3aR,5aR,6R,9aR,9bS)-3-({[2,5-Bis(trifluoromethyl)phenyl]carbamoyl}dodecahydro-3a,6-dimethyl-7-oxo-1H-benz[e]indene-6-propanoic acid; CAS 164656-20-6; 1H-Benz[e]indene-6-propanoic acid derivative; Trifluoromethylphenylamino carbonyl benzindene propanoic acid.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to confirm identity and purity. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research or development specifications. For cGMP-grade material or material manufactured under ISO 9001 quality systems, please contact our sales team for specific documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light) and should be handled with appropriate precautions for strong acid/organic solvent. Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.