Description

Dibenzyl N,n-Dimethylphosphoramidite is a specialized organophosphorus compound widely used as a key reagent in modern synthetic chemistry. Its primary value lies in its role as a versatile phosphitylating agent, crucial for the synthesis of complex phosphoramidites and nucleotides. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for oligonucleotide synthesis and catalyst development.

Application

• Oligonucleotide Synthesis: A critical reagent in the phosphoramidite method for constructing DNA and RNA strands.
• Phosphorus Ligand Precursor: Used in the preparation of chiral and achiral phosphorus ligands for asymmetric catalysis and cross-coupling reactions.
• Pharmaceutical Intermediates: Serves as a building block for active pharmaceutical ingredients (APIs) containing phosphorus, such as nucleotide analogs.
• Agrochemical Synthesis: Employed in the production of advanced pesticides and herbicides that utilize phosphoramidite chemistry.
• Material Science: Used in the surface modification of materials and the synthesis of phosphorus-containing polymers.
• Chemical Research & Development: A valuable tool for exploring new synthetic methodologies and creating novel organophosphorus compounds.

Basic Information

Product Name	Dibenzyl N,n-Dimethylphosphoramidite
CAS No.	164654-49-3
Molecular Formula	C16H20NO2P
Molecular Weight	289.31 g/mol
Synonyms	Dibenzyl Dimethylphosphoramidite; N,N-Dimethyl-P,P-dibenzylphosphoramidous Diamide; Phosphoramidous Acid, N,N-Dimethyl-, P,P-Dibenzyl Ester; (Dimethylamino)(dibenzyloxy)phosphine; DBDP; Dibenzyloxy(dimethylamino)phosphine
EINECS	Contact for details

Quality Control

Our Dibenzyl N,n-Dimethylphosphoramidite is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR and HPLC, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, well-ventilated area. This material is easily oxidized and moisture-sensitive; prolonged exposure to air or humidity should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.