Description

Boc-4-Amino-D-Phenylalanine (CAS 164332-89-2) is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound serves as a critical chiral building block, enabling the precise construction of complex peptide sequences with defined stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of the D-enantiomer of 4-aminophenylalanine into peptide chains.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Peptidomimetic Design: Facilitates the creation of modified peptides with enhanced stability, bioavailability, and receptor binding affinity.
• Bioconjugation: The aromatic amine group, once deprotected, provides a handle for site-specific labeling or coupling with other molecules (e.g., fluorophores, drugs, polymers).
• Chemical Biology Probes: Enables the synthesis of custom peptides for studying protein-protein interactions, enzyme mechanisms, and cellular pathways.
• Material Science: Can be incorporated into bio-inspired polymers and smart materials that respond to specific biological stimuli.

Basic Information

Product Name	Boc-4-Amino-D-Phenylalanine
CAS No.	164332-89-2
Molecular Formula	C₁₄H₂₀N₂O₄
Molecular Weight	280.32 g/mol
Synonyms	N-α-(tert-Butoxycarbonyl)-4-amino-D-phenylalanine; Boc-D-4-Aminophenylalanine; (R)-2-((tert-Butoxycarbonyl)amino)-3-(4-aminophenyl)propanoic acid; Boc-D-Phe(4-NH2)-OH; tert-Butyloxycarbonyl-4-amino-D-phenylalanine; Boc-4-NH2-D-Phe-OH; BOC-D-4-AMINOPHE; D-4-Aminophenylalanine, N-BOC-protected
EINECS	Contact for details

Quality Control

Our Boc-4-Amino-D-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (D-isomer)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.