Description

3,4-Difluorophenetole is a high-purity fluorinated aromatic ether building block of significant importance in advanced organic synthesis. Its molecular structure, featuring fluorine atoms on the phenetole ring, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and liquid crystal material industries.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, where the difluorophenetole moiety can enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a core building block for fluorine-containing liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Employed in the synthesis of advanced materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A valuable reagent for exploring new fluorination reactions and constructing complex aromatic ethers in academic and industrial labs.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, dyes, and functional polymers requiring specific fluorinated aromatic units.

Basic Information

Product Name	3,4-Difluorophenetole
CAS No.	163848-46-2
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	1-Ethoxy-3,4-difluorobenzene; 3,4-Difluorophenyl ethyl ether; Ethyl 3,4-difluorophenyl ether; 3,4-Difluoroanisole (common misnomer, correct is phenetole); Benzene, 1-ethoxy-3,4-difluoro-
EINECS	Contact for details

Quality Control

Our 3,4-Difluorophenetole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for sensitive synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical properties is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.