Description

Adrenomedullin (11-50) (Rat) is a specific bioactive peptide fragment derived from the full-length adrenomedullin hormone. This compound is of significant value for researchers investigating cardiovascular regulation, endocrine function, and related signaling pathways. It serves as a critical tool for biochemical research, pharmacological studies, and the development of diagnostic assays in the life sciences sector.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of adrenomedullin receptor binding and signal transduction mechanisms.
• Pharmacological Studies: Employed in in vitro and in vivo models to explore the vasodilatory, hypotensive, and other physiological effects of adrenomedullin fragments.
• Diagnostic Development: Serves as a key antigen or calibrator in the development and validation of immunoassays (e.g., ELISA) for detecting adrenomedullin-related peptides.
• Cell Culture & Physiology: Applied in cell-based assays to study the hormone's role in cellular proliferation, apoptosis, and metabolic processes.
• Neuroscience Research: Investigated for its potential neuromodulatory and neuroprotective effects within the central nervous system.

Basic Information

Product Name	Adrenomedullin (11-50) (Rat)
CAS No.	163648-32-6
Molecular Formula	C185H301N57O51S2
Molecular Weight	4253.9 g/mol
Synonyms	ADM (11-50), rat; Adrenomedullin fragment 11-50 (rat); rADM(11-50); H-Tyr-Arg-Gln-Ser-Met-Asn-Asn-Asn-Phe-Gln-Gly-Leu-Arg-Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2 (disulfide bridge: Cys17-Cys23); UNII-9K5V5V4Y0H
EINECS	Contact for details

Quality Control

Our Adrenomedullin (11-50) (Rat) is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. We adhere to rigorous quality testing protocols to meet the exacting standards required for biochemical and pharmacological research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	± 10% of theoretical
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.