Description

(2R)-1-[(4S)-4,5-Dihydro-4-(Phenylmethyl)-2-Oxazolyl]-2-(Diphenylphosphino)-Ferrocene is a highly specialized chiral ferrocenyl phosphine-oxazoline ligand, a critical component in asymmetric catalysis. Its value lies in enabling precise stereochemical control in transition metal-catalyzed reactions, leading to the efficient synthesis of enantiomerically pure compounds. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high-performance, tunable ligands for complex synthetic transformations.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for pharmaceutical intermediates.
• Catalyst component for enantioselective C-C and C-X bond-forming reactions.
• Key reagent in the synthesis of chiral natural products and active pharmaceutical ingredients (APIs).
• Use in asymmetric allylic substitution and hydrofunctionalization reactions.
• Research tool in organometallic chemistry and catalyst development for fine chemical synthesis.
• Component in catalyst systems for producing chiral agrochemicals and flavors/fragrances.

Basic Information

Product Name	(2R)-1-[(4S)-4,5-Dihydro-4-(Phenylmethyl)-2-Oxazolyl]-2-(Diphenylphosphino)-Ferrocene
CAS No.	163169-14-0
Molecular Formula	C32H28FeNOP
Molecular Weight	529.39 g/mol
Synonyms	Josiphos SL-J009-1; (R,S)-PPF-P(Ph)2; (R)-1-[(S)-4,5-Dihydro-4-(benzyl)-2-oxazolyl]-2-(diphenylphosphino)ferrocene; Ferrocenyl phosphine-oxazoline ligand; Chiral Josiphos-type ligand; (R)-[(S)-4-Benzyl-4,5-dihydro-2-oxazolyl](diphenylphosphino)ferrocene; (R,S)-PPF-PPh2; Asymmetric hydrogenation ligand J009-1
EINECS	Contact for details

Quality Control

Every batch of our (2R)-1-[(4S)-4,5-Dihydro-4-(Phenylmethyl)-2-Oxazolyl]-2-(Diphenylphosphino)-Ferrocene is subjected to rigorous analytical testing to ensure high purity and consistent performance as a chiral ligand. Our quality protocols are designed to meet the stringent requirements of advanced R&D and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and identity is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep the container sealed in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.