Description

(+/-)-Epibatidine Dihydrochloride is a high-purity, non-natural alkaloid derivative known for its potent and selective activity at nicotinic acetylcholine receptors. This compound is of significant value in advanced pharmacological research and neuroscience due to its unique biological profile. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in neuropharmacology, pain pathway studies, and the development of novel therapeutic agents.

Application

• Neuroscience Research: A critical tool for studying the structure and function of neuronal nicotinic acetylcholine receptors (nAChRs).
• Pharmacological Studies: Used as a reference standard and active compound in assays investigating receptor binding affinity, selectivity, and signal transduction.
• Analytical Chemistry: Serves as a certified reference material (CRM) for method development and validation in HPLC, LC-MS, and other analytical techniques.
• Drug Discovery: A key intermediate or pharmacological probe in the research and development of new analgesics and neurological therapeutics.
• Biochemical Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize new modulators of cholinergic pathways.
• Academic & Institutional Research: Used in university and government labs for fundamental research into pain mechanisms, addiction, and cognitive function.

Basic Information

Product Name	(+/-)-Epibatidine Dihydrochloride
CAS No.	162885-01-0
Molecular Formula	C11H13ClN2·2HCl
Molecular Weight	281.06 g/mol (Free base: 208.69)
Synonyms	(±)-Epibatidine Dihydrochloride; Epibatidine (±) Dihydrochloride; exo-2-(2-Chloro-5-pyridyl)-7-azabicyclo[2.2.1]heptane Dihydrochloride; 2-(6-Chloro-3-pyridinyl)-7-azabicyclo[2.2.1]heptane Dihydrochloride; (±)-exo-2-(6-Chloro-3-pyridinyl)-7-azabicyclo[2.2.1]heptane Dihydrochloride; Epibatidine Racemate Dihydrochloride; Epibatidine HCl
EINECS	Contact for details

Quality Control

Our (+/-)-Epibatidine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccant in the container.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.