Description

(S)-3,5-Dihydroxyphenylglycine is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. Its defined stereochemistry and functional groups make it a critical building block for the development of novel active pharmaceutical ingredients (APIs), particularly in neurological and metabolic research. This compound is essential for manufacturers and research institutions engaged in the development of enantiomerically pure drugs and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Neurological Research: Used in the development of compounds targeting neurotransmitter pathways and receptors.
• Metabolic Disorder Research: Serves as a building block for potential therapeutics for diabetes and related conditions.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to induce chirality.
• Peptidomimetics Development: Incorporated into the design of peptide-like molecules with enhanced stability and bioavailability.
• Chemical Biology Probes: Utilized in the creation of molecular tools for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	(S)-3,5-Dihydroxyphenylglycine
CAS No.	162870-29-3
Molecular Formula	C8H9NO4
Molecular Weight	183.16 g/mol
Synonyms	(S)-2-Amino-2-(3,5-dihydroxyphenyl)acetic acid; (S)-α-Amino-3,5-dihydroxybenzeneacetic acid; D-3,5-DHPG; (S)-3,5-DHPG; L-3,5-Dihydroxyphenylglycine; (S)-3,5-Dihydroxybenzene glycine; (S)-2-Amino-2-(3,5-dihydroxyphenyl)ethanoic acid
EINECS	Contact for details

Quality Control

Our (S)-3,5-Dihydroxyphenylglycine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, chiral purity, and impurity profiles as determined by advanced analytical techniques including HPLC and chiral chromatography. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.