Description

3-(n-Boc-Aminoethyl)Azetidine is a high-purity, protected amine building block essential for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular scaffolds to construct complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by pharmaceutical R&D teams, agrochemical developers, and specialty chemical companies engaged in peptide mimetics and heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in protease inhibitor and GPCR-targeted therapies.
• Peptidomimetic Chemistry: Serves as a constrained scaffold to mimic peptide secondary structures, enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides with specific mode-of-action targets.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Bioconjugation and Linker Chemistry: The Boc-protected amine and azetidine ring provide orthogonal reactivity for constructing bioconjugates and chemical probes.
• Material Science Research: Acts as a monomer or functionalization agent in the synthesis of polymers with tailored properties.

Basic Information

Product Name	3-(n-Boc-Aminoethyl)Azetidine
CAS No.	162696-31-3
Molecular Formula	C10H20N2O2
Molecular Weight	200.28 g/mol
Synonyms	1-Boc-3-(2-aminoethyl)azetidine; tert-Butyl 3-(2-aminoethyl)azetidine-1-carboxylate; 3-(2-((tert-Butoxycarbonyl)amino)ethyl)azetidine; 3-(2-Aminoethyl)azetidine-1-carboxylic acid tert-butyl ester; 3-(Boc-aminoethyl)azetidine; Azetidine, 3-(2-((1,1-dimethylethoxy)carbonyl)amino)ethyl]-; 1,1-Dimethylethyl 3-(2-aminoethyl)-1-azetidinecarboxylate
EINECS	Contact for details

Quality Control

Our 3-(n-Boc-Aminoethyl)Azetidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.