Description

1-Benzyl-4-(Hydroxymethyl)Piperidine-4-Carbonitrile is a versatile and high-value piperidine derivative, serving as a critical building block in advanced organic synthesis. Its unique bifunctional structure, featuring both a hydroxymethyl and a nitrile group on the same carbon, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS).
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its piperidine scaffold.
• Ligand and Catalyst Synthesis: Employed for constructing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Serves as a monomer or functional additive in the research of specialty polymers and advanced materials.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring functionalized piperidine cores.

Basic Information

Product Name	1-Benzyl-4-(Hydroxymethyl)Piperidine-4-Carbonitrile
CAS No.	162686-53-5
Molecular Formula	C14H18N2O
Molecular Weight	230.31 g/mol
Synonyms	4-(Hydroxymethyl)-1-benzylpiperidine-4-carbonitrile; 1-Benzyl-4-(hydroxymethyl)-4-piperidinecarbonitrile; 4-Cyano-1-benzyl-4-piperidinemethanol; 1-Benzyl-4-cyano-4-piperidinemethanol; 4-Piperidinecarbonitrile, 4-(hydroxymethyl)-1-(phenylmethyl)-; 1-Benzyl-4-(hydroxymethyl)piperidine-4-carbonitrile; (1-Benzylpiperidin-4-yl)(hydroxy)acetonitrile
EINECS	Contact for details

Quality Control

Our 1-Benzyl-4-(Hydroxymethyl)Piperidine-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications in GMP and ISO-certified environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.