Description

Boc-Tyr(Po3(Cl3Et)2)-Oh is a specialized, protected amino acid derivative featuring a phosphonate ester group. This compound is a critical building block in advanced organic synthesis, particularly for the development of peptide-based pharmaceuticals and biochemical probes. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs.

Application

• Peptide Synthesis: As a key intermediate for incorporating phosphotyrosine mimetics into peptide sequences, enabling the study of phosphorylation-dependent biological processes.
• Medicinal Chemistry: For the research and development of kinase inhibitors, signal transduction modulators, and other targeted therapeutic agents.
• Bioconjugation: Used in the preparation of labeled peptides and proteins for diagnostic assays and biochemical studies.
• Chemical Biology: Serves as a precursor for synthesizing activity-based probes to investigate enzyme function and protein-protein interactions.
• Pharmaceutical Intermediates: An essential raw material in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Boc-Tyr(Po3(Cl3Et)2)-Oh
CAS No.	162518-54-9
Molecular Formula	C₂₀H₂₉Cl₆NO₈P
Molecular Weight	637.03 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-O-[bis(2,2,2-trichloroethoxy)phosphoryl]tyrosine; Boc-O-(diphenoxyphosphoryl)tyrosine derivative; Boc-Tyr(PO(OCH₂CCl₃)₂)-OH; tert-Butyloxycarbonyl-O-phosphonotyrosine bis(2,2,2-trichloroethyl) ester; Boc-Phosphotyrosine(OC₂H₂Cl₃)₂; Protected Phosphotyrosine; Boc-Tyr(PO(OC₂H₂Cl₃)₂)-OH
EINECS	Contact for details

Quality Control

Our Boc-Tyr(Po3(Cl3Et)2)-Oh is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.