Description

5'-Deoxy-5'-N,n-Dimethylamino Thymidine is a modified nucleoside derivative, a key building block in advanced pharmaceutical and biochemical research. This compound is valued for its role as a versatile intermediate in the synthesis of novel antiviral agents, oligonucleotides, and other therapeutic molecules. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing next-generation nucleic acid-based therapies and diagnostics.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used in the development of modified antisense oligonucleotides and siRNA for therapeutic applications.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and DNA repair pathways.
• Prodrug Development: Utilized in creating prodrug forms of nucleoside pharmaceuticals to enhance bioavailability and targeting.
• Diagnostic Probe Synthesis: Incorporated into labeled probes for molecular diagnostics and genomic research.
• Academic & Industrial R&D: Fundamental material for exploring new chemical entities in medicinal chemistry programs.

Basic Information

Product Name	5'-Deoxy-5'-N,n-Dimethylamino Thymidine
CAS No.	162466-79-7
Molecular Formula	C12H19N3O5
Molecular Weight	285.30 g/mol
Synonyms	5'-Deoxy-5'-(dimethylamino)thymidine; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione; 5'-(Dimethylamino)-5'-deoxythymidine; Thymidine, 5'-deoxy-5'-(dimethylamino)-; 5'-N,N-Dimethylamino-5'-deoxythymidine; 5'-Deoxy-5'-(N,N-dimethylamino)thymidine
EINECS	Contact for details

Quality Control

Our 5'-Deoxy-5'-N,n-Dimethylamino Thymidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. We provide Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.