Description

(S,S)-1-(Dicyclohexylphosphino)-2-[1-(Diphenylphosphino)Ethyl]Ferrocene CAS NO 162291-01-2 is a highly specialized, chiral ferrocenyl phosphine ligand, a cornerstone in asymmetric catalysis. Its value lies in enabling highly enantioselective transformations, which are critical for the efficient and cost-effective synthesis of single-enantiomer pharmaceutical intermediates and fine chemicals. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control in hydrogenation, cross-coupling, and other transition metal-catalyzed reactions.

Application

• As a chiral ligand for asymmetric hydrogenation of prochiral olefins, ketones, and imines in pharmaceutical API synthesis.
• Catalyst component for enantioselective cross-coupling reactions (e.g., Suzuki-Miyaura, Heck) to construct chiral biaryl frameworks.
• Use in asymmetric allylic substitution reactions for the formation of carbon-carbon and carbon-heteroatom bonds with high enantiomeric excess.
• Key reagent in the development of homogeneous catalysts for the production of specialty chemicals and flavors & fragrances.
• Research and process development in academic and industrial laboratories focused on novel catalytic methodologies.
• Potential application in material science for creating chiral molecular architectures and polymers.

Basic Information

Item	Details
Product Name	(S,S)-1-(Dicyclohexylphosphino)-2-[1-(Diphenylphosphino)Ethyl]Ferrocene
CAS No.	162291-01-2
Molecular Formula	C36H44FeP2
Molecular Weight	594.52 g/mol
Synonyms	(S,S)-DuanPhos; (S,S)-1-[(Dicyclohexylphosphino)]-2-[(1-(diphenylphosphino)ethyl)]ferrocene; (S,S)-1-(Dicyclohexylphosphino)-2-[(1-(diphenylphosphino)ethyl)]ferrocene; (S,S)-1-(Dicyclohexylphosphanyl)-2-[1-(diphenylphosphanyl)ethyl]ferrocene; (S,S)-Dicyclohexyl[2-[1-(diphenylphosphino)ethyl]ferrocen-1-yl]phosphine; Josiphos-type ligand SL-J009-1; Chiral ferrocenyl diphosphine ligand
EINECS	Contact for details

Quality Control

Every batch of our chiral ligands is produced and tested under strict quality protocols to ensure consistency and performance in sensitive catalytic applications. We provide comprehensive Certificates of Analysis (COA) detailing purity, enantiomeric excess, and identity confirmation. Our quality system is designed to meet the exacting standards of GMP and ISO environments for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C or as specified on the label. This compound is easily oxidized; prolonged exposure to air or moisture should be avoided to maintain ligand efficacy.

Specification

Item	Specification
Appearance	Orange to red powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.