Description

2,6-Difluorophenylboronic Acid is a high-purity organoboron compound, a key building block in modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through pivotal cross-coupling reactions, such as the Suzuki-Miyaura reaction. This boronic acid is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to introduce the valuable 2,6-difluorophenyl moiety into target structures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides, where the difluorophenyl group enhances biological activity and stability.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: The principal reagent for forming carbon-carbon bonds between aryl halides and this boronic acid, facilitating the creation of biaryl structures.
• Chemical Research & Development: A versatile tool in medicinal chemistry and process chemistry for lead optimization and scale-up synthesis.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2,6-Difluorophenylboronic Acid
CAS No.	162101-25-9
Molecular Formula	C6H5BF2O2
Molecular Weight	157.92 g/mol
Synonyms	(2,6-Difluorophenyl)boronic Acid; B-(2,6-Difluorophenyl)boronic Acid; 2,6-Difluorobenzeneboronic Acid; 2,6-Difluorophenyl-Boronic Acid; Boronic acid, B-(2,6-difluorophenyl)-; 2,6-DFPBA
EINECS	Contact for details

Quality Control

Our 2,6-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring material traceability and compliance with cGMP and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Melting Point	Contact for details
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.