Description

Bicyclo[2.2.1]Heptane, 2,2-Difluoro-6-Methyl- (9Ci) is a specialized fluorinated bicyclic organic compound, serving as a valuable building block in advanced synthetic chemistry. Its unique structure, featuring a rigid norbornane core with fluorine and methyl substituents, makes it a critical intermediate for developing novel materials and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific steric and electronic properties into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and antiviral research, where the fluorine atom can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the bicyclic framework contributes to unique biological activity and environmental persistence profiles.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers, resins, and liquid crystals with tailored thermal and optical properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel chiral ligands and catalysts for asymmetric synthesis, leveraging its three-dimensional geometry.
• Fluorine Chemistry Research: A valuable reference compound and starting material in academic and industrial R&D focused on exploring new C-F bond formation reactions and fluorine effects.
• Electronic Chemicals: Potential use in the synthesis of dielectric fluids, etching agents, or precursors for semiconductor manufacturing due to its fluorinated structure.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane, 2,2-Difluoro-6-Methyl- (9Ci)
CAS No.	161716-74-1
Molecular Formula	C8H12F2
Molecular Weight	146.18 g/mol
Synonyms	2,2-Difluoro-6-methylbicyclo[2.2.1]heptane; 6-Methyl-2,2-difluoronorbornane; 2,2-Difluoro-6-methylnorbornane; 1,3,3-Trimethyl-2,2-difluorobicyclo[2.2.1]heptane; 2,2-Difluoro-1,3,3-trimethylnorbornane; 2,2-Difluoro-6-methyl-1,3,3-trimethylenenorbornane (related structural names); Contact for additional IUPAC and trade names.
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane, 2,2-Difluoro-6-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical properties. Our production adheres to cGMP guidelines where applicable, ensuring reliable consistency and traceability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0% (Area %)
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.