Description

tert-Butyl 1-(Methoxy(Methyl)Carbamoyl)Cyclopropylcarbamate is a specialized carbamate-protected cyclopropane derivative, serving as a crucial synthetic intermediate in advanced organic synthesis. Its value lies in its role as a protected amine building block, enabling the controlled construction of complex molecular architectures with high stereochemical fidelity. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs) and novel agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those containing cyclopropane or constrained peptide motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that require specific, rigid molecular frameworks.
• Peptidomimetics Research: Facilitates the creation of cyclopropane-containing amino acid analogs for drug discovery programs targeting protease inhibition.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	tert-Butyl 1-(Methoxy(Methyl)Carbamoyl)Cyclopropylcarbamate
CAS No.	161521-10-4
Molecular Formula	C12H22N2O4
Molecular Weight	258.31 g/mol
Synonyms	1-[[(1,1-Dimethylethoxy)carbonyl]amino]cyclopropanecarboxylic acid, N-methoxy-N-methylamide; N-Boc-1-aminocyclopropanecarboxylic acid N-methoxy-N-methylamide; 1-[(tert-Butoxycarbonyl)amino]cyclopropanecarboxylic acid N-methoxy-N-methylamide; Boc-ACCA-N-OMe, N-Me; tert-Butyl N-[1-[(methoxy(methyl)carbamoyl)cyclopropyl]carbamate; Cyclopropanecarboxamide, 1-[[(1,1-dimethylethoxy)carbonyl]amino]-N-methoxy-N-methyl-
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-(Methoxy(Methyl)Carbamoyl)Cyclopropylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP (Good Manufacturing Practice) and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.