Description

L-Isoleucine, n-[(1,1-Dimethylethoxy)Carbonyl]-3-Methyl- (9Ci) is a protected derivative of the essential amino acid L-Isoleucine, featuring a tert-butoxycarbonyl (Boc) protecting group on the amine functionality. This compound is of critical importance in peptide synthesis and pharmaceutical research, where it serves as a key building block for constructing complex peptides and protein mimetics with high stereochemical purity. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the production of therapeutic peptides, bioactive compounds, and advanced materials.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental Boc-protected amino acid for the sequential assembly of peptides, ensuring controlled coupling and preventing unwanted side reactions.
• Pharmaceutical Intermediate: Used in the research and development of novel peptide-based drugs, including hormones, enzyme inhibitors, and antimicrobial agents.
• Bioconjugation and Labeling: Serves as a precursor for introducing the isoleucine residue into proteins or other biomolecules for structural studies or diagnostic applications.
• Chemical Biology Research: Employed in the synthesis of peptide libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Production of Custom Peptides: Essential for contract research and manufacturing organizations (CROs/CMOs) producing bespoke peptides for clients in academia and industry.
• Nutraceutical Research: Used in advanced studies exploring modified amino acids and their potential bioactive benefits.

Basic Information

Product Name	L-Isoleucine, n-[(1,1-Dimethylethoxy)Carbonyl]-3-Methyl- (9Ci)
CAS No.	161479-50-1
Molecular Formula	C11H21NO4
Molecular Weight	231.29 g/mol
Synonyms	Boc-L-Isoleucine; N-Boc-L-Isoleucine; (2S,3S)-2-[(tert-Butoxycarbonyl)amino]-3-methylpentanoic acid; N-(tert-Butoxycarbonyl)-L-isoleucine; Boc-Ile-OH; BOC-ILE; N-α-Boc-L-isoleucine; L-Isoleucine, N-[(1,1-dimethylethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our Boc-L-Isoleucine is manufactured under strict quality control protocols to ensure it meets the high-purity standards required for sensitive synthetic applications. Each batch is tested for identity, purity, and chiral integrity using advanced analytical techniques. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) and optical rotation values are provided to guarantee consistent quality and traceability for your research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Optical Rotation [α]	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.