Description

Adrenomedullin (Rat) is a potent, biologically active peptide hormone. It plays a critical role in cardiovascular regulation, vasodilation, and as an endogenous antimicrobial peptide, making it a valuable tool for cardiovascular and sepsis research. This high-purity peptide is essential for researchers and developers in the fields of pharmacology, molecular biology, and preclinical drug discovery. It is supplied as a lyophilized powder to ensure stability and ease of reconstitution for experimental use.

Application

• Cardiovascular Research: Used to study vasodilation, blood pressure regulation, and endothelial function in rat models.
• Sepsis and Inflammation Studies: Investigated for its role as an endogenous antimicrobial peptide and its effects on inflammatory pathways.
• Receptor Binding Assays: Serves as a high-affinity ligand for studying adrenomedullin receptor (AM1/AM2) interactions and signaling.
• Biomarker Development: Utilized in the development of immunoassays (ELISA, RIA) to measure adrenomedullin levels in biological samples.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to examine its effects on cell proliferation, apoptosis, and cytokine release.
• Peptide Chemistry Reference: Acts as a reference standard for purity and identity in analytical method development and quality control.

Basic Information

Product Name	Adrenomedullin (Rat)
CAS No.	161383-47-7
Molecular Formula	C174H283N55O51S
Molecular Weight	4064.6 g/mol
Synonyms	Rat Adrenomedullin; ADM (Rat); Adrenomedullin (1-50), rat; AM (Rat); H-Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2 (Disulfide bridge: Cys16-Cys21); UNII-8V5Q8Q88QN
EINECS	Contact for details

Quality Control

Every batch of Adrenomedullin (Rat) is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure high purity and batch-to-batch consistency suitable for research applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.