Description

Cyclopropanecarbonitrile, 2-Ethoxy-1-(Phenylthio)-, trans- (9Ci) is a specialized organic compound featuring a cyclopropane ring substituted with ethoxy, phenylthio, and nitrile functional groups. This unique molecular architecture makes it a valuable and versatile chiral building block in advanced synthetic chemistry. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for constructing active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting novel therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents and pesticides, leveraging its stereochemistry.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrances, flavors, and other high-value specialty chemicals.
• Academic & Industrial R&D: A critical reagent for methodological studies in organic synthesis, enabling the exploration of new cyclopropanation and functionalization reactions.

Basic Information

Product Name	Cyclopropanecarbonitrile, 2-Ethoxy-1-(Phenylthio)-, trans- (9Ci)
CAS No.	161262-85-7
Molecular Formula	C₁₂H₁₃NOS
Molecular Weight	219.30 g/mol
Synonyms	trans-2-Ethoxy-1-(phenylthio)cyclopropanecarbonitrile; (1R,2S)-rel-2-Ethoxy-1-(phenylthio)cyclopropanecarbonitrile; 2-Ethoxy-1-(phenylthio)cyclopropanecarbonitrile; 1-(Phenylthio)-2-ethoxycyclopropanecarbonitrile; Cyclopropanecarbonitrile, 1-(phenylthio)-2-ethoxy-, trans-; 161262-85-7; (1S,2R)-2-Ethoxy-1-(phenylsulfanyl)cyclopropane-1-carbonitrile
EINECS	Contact for details

Quality Control

Our Cyclopropanecarbonitrile, 2-Ethoxy-1-(Phenylthio)-, trans- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term stability, it is recommended to store the product at 2-8°C under an inert atmosphere. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.