Description

2-Propanone, 3-Cyclopropyl-1,1,1-Trifluoro- is a specialized fluorinated ketone building block, identified by CAS number 161237-00-9. This compound matters for its unique trifluoromethyl and cyclopropyl functional groups, which are critical for modulating the lipophilicity, metabolic stability, and biological activity of advanced molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for introducing the trifluoromethylcyclopropyl moiety into drug candidates, particularly in medicinal chemistry for CNS and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorinated cyclopropyl group enhances compound efficacy and environmental profile.
• Advanced Material Precursor: Serves as a building block for specialty polymers and liquid crystals that require specific fluorine-containing segments.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for cyclopropanation reactions and as a versatile fluorinated acetone derivative.
• Fluorine Chemistry Research: Essential for studying structure-activity relationships (SAR) in fluorinated compounds.

Basic Information

Product Name	2-Propanone, 3-Cyclopropyl-1,1,1-Trifluoro-
CAS No.	161237-00-9
Molecular Formula	C6H7F3O
Molecular Weight	152.11 g/mol
Synonyms	3-Cyclopropyl-1,1,1-trifluoroacetone; 1,1,1-Trifluoro-3-cyclopropylpropan-2-one; 3-Cyclopropyl-1,1,1-trifluoropropan-2-one; Trifluoro(cyclopropyl)acetone; (Cyclopropyl)trifluoroacetone; 3-Cyclopropyl-1,1,1-trifluoro-2-propanone; 3-Cyclopropyl-1,1,1-trifluoroacetone (primary synonym)
EINECS	Contact for details

Quality Control

Every batch of 2-Propanone, 3-Cyclopropyl-1,1,1-Trifluoro- is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for research chemicals. Comprehensive analytical testing, including GC, HPLC, and NMR, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and specification adherence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, keep away from heat, sparks, and open flame. Ensure containers are kept tightly sealed when not in use to prevent evaporation and potential contamination.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.