Description

2-Bromo-4-Hydroxy-5-Methoxy-Benzonitrile is a versatile benzonitrile derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated and substituted aromatic structure makes it valuable for constructing complex molecules with specific electronic and steric properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors or other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its halogen and nitrile functionality.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, or organic electronic materials due to its rigid, substituted aromatic core.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and enzyme activity.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Bromo-4-Hydroxy-5-Methoxy-Benzonitrile
CAS No.	161196-87-8
Molecular Formula	C9H6BrNO2
Molecular Weight	240.05 g/mol
Synonyms	5-Methoxy-2-bromo-4-hydroxybenzonitrile; 4-Hydroxy-5-methoxy-2-bromobenzonitrile; 2-Bromo-4-hydroxy-5-methoxybenzonitrile; Benzonitrile, 2-bromo-4-hydroxy-5-methoxy-; 2-Bromo-5-methoxy-4-hydroxybenzonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Hydroxy-5-Methoxy-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.