Description

Isoxazole, 4-Methyl-5-(Trifluoromethyl)- (9Ci) is a specialized heterocyclic organic compound featuring a core isoxazole ring substituted with methyl and trifluoromethyl groups. This molecular structure makes it a valuable and versatile building block in advanced organic synthesis, particularly for introducing fluorine-containing motifs. It is primarily utilized by pharmaceutical and agrochemical research and development teams to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a core structure in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the isoxazole ring and the metabolic stability imparted by the trifluoromethyl group.
• Material Science Research: Used in the synthesis of specialty polymers, liquid crystals, and electronic materials where fluorine substitution can alter physical properties like solubility, thermal stability, and dielectric constant.
• Chemical Biology & Proteomics: Employed as a labeling reagent or a scaffold for designing chemical probes to study enzyme function and protein interactions.
• Organic Synthesis Building Block: Facilitates the construction of complex molecules for discovery chemistry in both academic and industrial settings.

Basic Information

Product Name	Isoxazole, 4-Methyl-5-(Trifluoromethyl)- (9Ci)
CAS No.	161144-76-9
Molecular Formula	C5H4F3NO
Molecular Weight	151.09 g/mol
Synonyms	4-Methyl-5-(trifluoromethyl)isoxazole; 5-(Trifluoromethyl)-4-methylisoxazole; 4-Methyl-5-trifluoromethylisoxazole; 4-Methyl-5-(trifluoromethyl)-1,2-oxazole; 1,2-Oxazole, 4-methyl-5-(trifluoromethyl)-; Isoxazole, 4-methyl-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our Isoxazole, 4-Methyl-5-(Trifluoromethyl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.