Description

1,2-Cyclohexanedicarbonyl Difluoride, cis- (9Ci) is a high-purity, reactive fluorinated building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing complex drug candidates, especially those requiring fluorinated motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the introduction of fluorine atoms can improve efficacy and environmental profile.
• Material Science Research: Serves as a monomer or precursor for developing novel fluorinated polymers and specialty materials with unique surface properties.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated ligands and organocatalysts for asymmetric synthesis and other specialized chemical transformations.
• Fluorination Reagent: Acts as a source of the difluoromethylene (-CF2-) unit in multi-step synthetic routes to introduce fluorinated functional groups.

Basic Information

Product Name	1,2-Cyclohexanedicarbonyl Difluoride, cis- (9Ci)
CAS No.	161117-13-1
Molecular Formula	C8H10F2O2
Molecular Weight	176.16 g/mol
Synonyms	cis-1,2-Cyclohexanedicarboxylic Acid Difluoride; cis-Cyclohexane-1,2-dicarbonyl Difluoride; 1,2-cis-Cyclohexanedicarbonyl Difluoride; cis-Hexahydrophthaloyl Difluoride; cis-Perhydrophthaloyl Difluoride; (1R,2S)-rel-Cyclohexane-1,2-dicarbonyl Difluoride; Cyclohexane-1,2-dicarboxylic Acid, cis-, Difluoride
EINECS	Contact for details

Quality Control

Our 1,2-Cyclohexanedicarbonyl Difluoride, cis- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.