Description

2-Butanone, 1,1,1-Trifluoro-3-Hydroxy- (9Ci) is a fluorinated derivative of butanone, characterized by the presence of a trifluoromethyl group and a hydroxyl moiety. This unique structure makes it a valuable specialty fluorinated building block for advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the fine chemical and life science industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group is a critical functional group.
• Liquid Crystal & Electronic Chemicals: Serves as a precursor in the manufacturing of fluorinated compounds for electronic applications and display technologies.
• Advanced Material Research: Employed in polymer science to introduce fluorine-containing side chains, altering material properties like surface energy and chemical resistance.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes for constructing complex molecules in academic and industrial research laboratories.

Basic Information

Product Name	2-Butanone, 1,1,1-Trifluoro-3-Hydroxy- (9Ci)
CAS No.	161084-30-6
Molecular Formula	C4H5F3O2
Molecular Weight	142.08 g/mol
Synonyms	1,1,1-Trifluoro-3-hydroxybutan-2-one; 3-Hydroxy-1,1,1-trifluorobutan-2-one; 1,1,1-Trifluoro-3-hydroxy-2-butanone; TFHB; Trifluoromethyl hydroxybutanone; 3-Hydroxy-1,1,1-trifluoro-2-butanone; 2-Butanone, 1,1,1-trifluoro-3-hydroxy-
EINECS	Contact for details

Quality Control

Our 2-Butanone, 1,1,1-Trifluoro-3-Hydroxy- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, NMR, and FTIR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality documentation to meet specific client and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Due to its highly volatile nature, keep away from heat, sparks, and open flame. The container must be kept tightly sealed when not in use to prevent evaporation and potential moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Impurities (HPLC)	Individually ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.