Description

Hcv-1 E2 Protein (484-499) is a synthetic peptide fragment corresponding to a specific epitope of the Hepatitis C Virus (HCV) envelope glycoprotein E2. This high-purity research-grade peptide is critical for immunological studies, assay development, and vaccine research targeting HCV. It is primarily utilized by biotechnology and pharmaceutical companies, as well as academic research institutions, engaged in virology, immunology, and therapeutic discovery. The product is supplied with CAS No. 161012-10-8.

Application

• Immunological Research: Used as an antigen for studying antibody responses and B-cell epitope mapping related to HCV infection.
• Diagnostic Assay Development: Serves as a key component in the development and validation of ELISA and other immunoassays for HCV antibody detection.
• Vaccine Research: Employed in preclinical studies to evaluate immunogenicity and efficacy of potential HCV vaccine candidates.
• Antibody Production & Screening: Acts as an immunogen for generating monoclonal or polyclonal antibodies specific to the HCV E2 protein.
• Binding Studies: Utilized in surface plasmon resonance (SPR) or other biophysical techniques to investigate interactions with host cell receptors or neutralizing antibodies.
• Quality Control Reference: Functions as a reference standard in the quality control of diagnostic kits and other biological reagents.

Basic Information

Product Name	Hcv-1 E2 Protein (484-499)
CAS No.	161012-10-8
Molecular Formula	C79H122N20O24S
Molecular Weight	1759.0 g/mol
Synonyms	HCV E2 (484-499) Peptide; Hepatitis C Virus Envelope Glycoprotein E2 Fragment (484-499); HCV-1 E2 (484-499); HCV E2 Epitope; HCV Envelope Protein Peptide; ASLLAPITAYAQQTRG; Hcv-1 E2 (484-499) Protein Fragment
EINECS	Contact for details

Quality Control

Every batch of Hcv-1 E2 Protein (484-499) is manufactured and tested under stringent conditions to ensure the highest standards of purity and consistency for research applications. Identity is confirmed by mass spectrometry (MS) and HPLC, with purity typically exceeding 95% as determined by analytical HPLC. Our products undergo rigorous quality testing, and comprehensive Certificates of Analysis (COA) detailing purity, sequence verification, and endotoxin levels are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This peptide is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. Aliquot into single-use vials to minimize freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Amino Acid Sequence	ASLLAPITAYAQQTRG
Peptide Content	≥ 70% (by weight)
Solubility	Soluble in water or dilute aqueous acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.