Description

n-Fmoc-4-(Methylamino)Benzoic Acid is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled introduction of modified aromatic amino acid structures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptide-based therapeutics, diagnostics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the incorporation of 4-(methylamino)benzoic acid residues into peptide chains.
• Pharmaceutical Research: Used in the discovery and development of peptide drugs, hormone analogs, and targeted bioactive molecules.
• Combinatorial Chemistry: Serves as a versatile scaffold for generating diverse chemical libraries for high-throughput screening.
• Bioconjugation: Facilitates the site-specific labeling and modification of peptides and proteins for diagnostic and research applications.
• Material Science: Can be employed in the synthesis of specialized polymers and advanced organic materials with tailored properties.

Basic Information

Product Name	n-Fmoc-4-(Methylamino)Benzoic Acid
CAS No.	160977-92-4
Molecular Formula	C23H19NO4
Molecular Weight	373.40 g/mol
Synonyms	Fmoc-4-(Methylamino)benzoic acid; 4-[(9H-Fluoren-9-ylmethoxy)carbonyl](methyl)amino]benzoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-4-aminobenzoic acid; N-Fmoc-N-methyl-p-aminobenzoic acid; Fmoc-Me-4-Abz-OH; Fmoc-N-Me-4-Abz-OH; Nα-Fmoc-Nα-methyl-4-aminobenzoic acid
EINECS	Contact for details

Quality Control

Our n-Fmoc-4-(Methylamino)Benzoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material traceability documentation upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.