Description

6-Chloro-5-Nitronicotinonitrile is a versatile and high-value nitrile-substituted pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and nitro substituents adjacent to the nitrile group, makes it an essential precursor for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This intermediate is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the creation of new herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Material Science Precursor: Serves as a starting material for the development of specialized ligands, dyes, and photoactive compounds.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic aromatic substitutions, and cyclization reactions to create complex heterocycles.
• Research & Development: An important reagent in academic and industrial R&D labs for exploring new chemical spaces and reaction methodologies.

Basic Information

Product Name	6-Chloro-5-Nitronicotinonitrile
CAS No.	160906-98-9
Molecular Formula	C6H2ClN3O2
Molecular Weight	183.55 g/mol
Synonyms	5-Nitro-6-chloronicotinonitrile; 6-Chloro-5-nitropyridine-3-carbonitrile; 3-Cyano-6-chloro-5-nitropyridine; 6-Chloro-5-nitro-3-pyridinecarbonitrile; 2-Chloro-5-cyano-3-nitropyridine; 160906-98-9; Nicotinonitrile, 6-chloro-5-nitro-
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-Nitronicotinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.