Description

(S)-2-Hydroxy-3-Heptynenitrile CAS NO 160754-12-1 is a chiral, non-racemic organic compound featuring both a hydroxyl group and a nitrile functionality on an alkyne backbone. This unique structural motif makes it a valuable chiral building block and synthetic intermediate for the preparation of complex, optically active molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries. The compound's defined stereochemistry is critical for applications requiring high enantiomeric purity in final products.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of novel, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Synthesis: Acts as a precursor for the preparation of chiral ligands and organocatalysts used in asymmetric transformations.
• Natural Product Synthesis: Employed in the total synthesis of complex natural products where the specific stereochemistry of the 2-hydroxy nitrile moiety is required.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating specialized polymers with unique optical or mechanical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	(S)-2-Hydroxy-3-Heptynenitrile
CAS No.	160754-12-1
Molecular Formula	C7H9NO
Molecular Weight	123.15 g/mol
Synonyms	(S)-2-Hydroxyhept-3-ynenitrile; (2S)-2-Hydroxy-3-heptynenitrile; (S)-2-Hydroxy-3-heptynenitrile; 3-Heptynenitrile, 2-hydroxy-, (2S)-; (S)-2-Hydroxy-3-heptynenitrile; (S)-2-Hydroxy-hept-3-ynenitrile; (S)-2-Hydroxy-3-heptynenitrile (enantiomer)
EINECS	Contact for details

Quality Control

Our (S)-2-Hydroxy-3-Heptynenitrile is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment, supporting cGMP and ISO 9001 compliant workflows for our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.