Description

(R)-4-Phenyl-3-Propionyl-2-Oxazolidinone is a high-value chiral auxiliary and synthetic building block of significant importance in asymmetric organic synthesis. Its core value lies in enabling the stereoselective production of enantiomerically pure compounds, which is critical for developing active pharmaceutical ingredients (APIs) and advanced agrochemicals. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-purity chiral reagents.

Application

• Asymmetric Synthesis: Employed as a versatile chiral auxiliary for the enantioselective alkylation, aldol, and Michael addition reactions.
• Pharmaceutical Intermediates: A key building block in the synthesis of complex, biologically active molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the research and production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Catalyst and Ligand Preparation: Serves as a precursor for the synthesis of novel chiral catalysts and ligands used in homogeneous catalysis.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic chemistry and process optimization studies.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals where precise stereochemistry dictates function and performance.

Basic Information

Product Name	(R)-4-Phenyl-3-Propionyl-2-Oxazolidinone
CAS No.	160695-26-1
Molecular Formula	C12H13NO3
Molecular Weight	219.24 g/mol
Synonyms	(R)-4-Phenyl-3-propionyloxazolidin-2-one; (R)-3-Propionyl-4-phenyl-2-oxazolidinone; (R)-N-Propionyl-4-phenyloxazolidin-2-one; (R)-4-Phenyl-3-(1-oxopropyl)-2-oxazolidinone; (R)-(-)-4-Phenyl-3-propionyl-2-oxazolidinone; Evans Auxiliary (Propionyl variant); (R)-Propionyl Evans Auxiliary
EINECS	Contact for details

Quality Control

Our (R)-4-Phenyl-3-Propionyl-2-Oxazolidinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for asymmetric synthesis. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.