Description

4-Chloro-2-Fluorophenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. This compound matters for its crucial role as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is primarily needed by pharmaceutical R&D teams, agrochemical manufacturers, and advanced material scientists for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Material Science: Serves as a precursor for creating specialized polymers, liquid crystals, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: The primary application, facilitating carbon-carbon bond formation to create complex, functionalized biaryl compounds.
• Chemical Research & Development: Employed in academic and industrial labs for methodological development and library synthesis.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Chloro-2-Fluorophenylboronic Acid
CAS No.	160591-91-3
Molecular Formula	C6H5BClFO2
Molecular Weight	173.37 g/mol
Synonyms	(4-Chloro-2-fluorophenyl)boronic acid; 2-Fluoro-4-chlorophenylboronic acid; 4-Chloro-2-fluorobenzeneboronic acid; B-(4-Chloro-2-fluorophenyl)boronic acid; 160591-91-3; 4-Chloro-2-fluoro-benzeneboronic acid; (4-Chloro-2-fluoro-phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing lot-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.