Description

3-Amino-n-[(1,1-Dimethylethoxy)Carbonyl]- Dl-Phenylalanine is a protected amino acid derivative, specifically a Boc-protected phenylalanine analog, serving as a critical chiral building block in advanced organic synthesis. Its primary value lies in enabling the controlled synthesis of complex peptides and peptidomimetics, where the Boc group provides orthogonal protection for the amine functionality. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the development of active pharmaceutical ingredients (APIs), peptide-based therapeutics, and novel drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected amino acid building block for constructing peptide chains.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled peptides, fluorescent probes, and other bioconjugates for diagnostic and research applications.
• Chemical Biology Research: Employed in the design and synthesis of peptidomimetics, enzyme inhibitors, and other bioactive compounds for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis providers and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	3-Amino-n-[(1,1-Dimethylethoxy)Carbonyl]- Dl-Phenylalanine
CAS No.	160560-73-6
Molecular Formula	C₁₄H₂₀N₂O₄
Molecular Weight	280.32 g/mol
Synonyms	Boc-3-amino-DL-phenylalanine; tert-Butyl (3-amino-1-carboxy-3-phenylpropyl)carbamate; DL-3-Amino-N-Boc-phenylalanine; (RS)-3-Amino-N-(tert-butoxycarbonyl)phenylalanine; 3-Amino-N-Boc-DL-phenylalanine; N-(tert-Butoxycarbonyl)-3-amino-DL-phenylalanine; 3-Amino-N-Boc-phenylalanine, DL-; Boc-Phe(3-NH2)-OH
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical applications. Each batch is characterized using advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) are available upon request, providing full transparency on batch-specific specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.